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    Using the mechanical anastomosis method has many advantages over hand-stitching:
    1. Fast and efficient;
    2. Better maintenance of hemostasis;
    3. Better effectiveness entering tissue;
    4. Better strength and durability;
    5. Not prone to infection;
    6. Lower risk of cancer recurrence;
    7. Easier to use;
    8. Better results for the patient.

    Bleeding ...
    Compared with the traditional suture ligation, in complete resection carried out using an anastomat "... estimated blood loss was significantly lower, so only a relatively small amount of blood transfusion was necessary..."

     Low risk of infection ...
    In an analysis of 62 cases of caesarean sections, the non-anastomosis group showed "... postoperative anemia, endometriosis and urinary tract infections ...". Staple material is less reactive than other suture material, and "... it is not likely to increase infection."

    Durability ...
    Titanium staples used for anastomosis are "... the most ideal tissue attachment material ..." and can provide better strength. An animal experiment comparing the use of an anastomat in surgery with using interrupted Dacron suture surgery found that "... the breaking strength was 6 times greater using anastomosis in canine colon surgery..."

    In cancer cases ...
    "... it was found that malignant cells attached to suture material ..." The two experiments showed that after cancer resection, anastomosis staples "... reduce anastomotic recurrence rate by 40%, and reduce cancer-specific incidence rate by 50%." “The use of anastomosis in end to end ileum colon anastomosis is related with a low complication rate and anastomosis recurrence rate. "

    Anastomotic leak rate ...
    In cervical esophagogastrostomy, anastomosis shows "... significantly lower rates of leakage, swallowing difficulties and complications..." Compared with hand-stitching, this method may be preferred. Weissberg found lower leakage rates in subperitoneal colorectal anastomosis than with the use of sutures

    Mortality rate …
    Among 250 patients with gastric cancer resection, the "... mortality from fistulas caused by esophageal jejunostomy was significantly higher with hand-stitching." In another experiment, "... 3.4% of patients died within 30 days after suture anastomosis, 2 cases were caused by anastomotic leakage. "

    Stenosis …
    In rectal resection in rectal adenocarcinoma and total mesorectal excision, "... with hand-stitching, 3 patients exhibited anastomotic stenosis, but none of the patients in the anastomosis group did." For distal gastrectomy in gastric and duodenal stomach bowel resection, the experiment concluded that "... Compared with hand-stitching, the probability of anastomotic stenosis using stapling anastomosis appears low." Another experiment found that postoperative ileus occurred less frequently after anastomosis closure of ileectomy.
    High speed …
    "Staple anastomosis of the colon is significantly faster than hand-stitching... The mean operation time is 53 minutes shorter ..." and costs are saved as well. Another experiment concluded that staple anastomosis used in gastroduodenal anastomosis was "... faster than hand-stitching, with an average time of 14 minutes compared to 25."